RNA Details
Disease Name
endomyocardial fibrosis
Tissue
heart
RNA Symbol
Gas5
RNA ID
RNA Type
lncrna
Alteration Pattern
up regulation
Species
mus musculus
Detection Methods
qRT-PCR; cell counting kit-8 analysis etc.
Target
HMGB1
Pathway
NF-KAPPA B SIGNALING PATHWAY
PubMed ID
Title
Downregulation of growth arrest-specific transcript 5 alleviates palmitic acid-induced myocardial inflammatory injury through the miR-26a/HMGB1/NF-KB axis
Year
2018
Function
Palmitic acid (PA) can induce gas5 expression and that the downregulation of gas5 alleviated pa-induced myocardial inflammatory injury through the miR-26a/HMGB1/NF-KB axis.